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AwardedAwarded 24 August 2026

Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service

NHS England · NHS and health

In brief

NHS England awarded healthcare work to Northern Care Alliance NHS Foundation Trust, Great Ormond Street Hospital and Guy's and St Thomas' NHS Foundation Trust and 13 others on 24 August 2026.

The notice gives a value of £26,136,000 excluding VAT.

It is split into 5 lots, so a supplier can bid for part of the work.

Built from the notice's own fields. Always check the official notice before you bid.

What the notice says

Intention to award the Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service. <br/><br/>This is a a one-time, in vivo gene replacement therapy, for use in babies aged 12 months and under, that utilises an adeno-associated virus serotype 9 (AAV9) vector, modified to contain a functional copy of the human SMN1 gene. It is administered intravenously, allowing the vector to deliver the gene into motor neurones and peripheral tissues, enabling the sustained expression of survival motor neuron (SMN) protein, which is deficient or mutated in individuals with SMA.<br/><br/>Onasemnogene abeparvovec intrathecal (OAV101 IT) is a one-time in vivo gene replacement therapy for patients with SMA, proposed to treat individuals with SMA aged 2 years and over. This intrathecal injection will be used to treat a distinct cohort of SMA patients to Zolgensma. It will be assessed via NICE’s technology appraisal programme, with an expected final guidance publication date in late 2026.<br/><br/>Procurement was carried out in Lots for the services as detailed above. Contract values are estimated and will be dependent on number of patients actually treated at each awarded provider.

Lots

LotTradeValue
Lot 1
What this lot covers

Lot 1: Zolgensma only (if no positive NICE recommendation for OAV101 IT)

Healthcare services£8,527,000
Lot 3
What this lot covers

Lot 3: Positive NICE recommendation for OAV101 IT for adult patients (either standalone or in combination with Lots 1 and 2) Additional information: Lot 3: Positive NICE recommendation for OAV101 IT for adult patients (either standalone or in combination with Lots 1 and 2)

Healthcare services£8,283,000
Lots 3
What this lot covers

Lot 3: Positive NICE recommendation for OAV101 IT for adult patients (either standalone or in combination with Lots 1 and 2)

Healthcare services£9,326,000
Lot 1
What this lot covers

Lot 1: Zolgensma only (if no positive NICE recommendation for OAV101 IT)

Healthcare services—
Lot 2
What this lot covers

Lot 2: Positive recommendation for OAV101 IT for paediatric patients (in combination with Lot 1 for Zolgensma)

Healthcare services—

Who won

WinnerLotValueDates
Northern Care Alliance NHS Foundation Trust—£1,036,000
Great Ormond Street Hospital—£776,000
Guy's and St Thomas' NHS Foundation Trust (SME)—£776,000
University Hospitals Bristol and Weston NHS Foundation Trust—£776,000
University Hospitals of North Staffordshire NHS Trust—£776,000
Sheffield Children's NHS Foundation Trust—£776,000
Leeds Teaching Hopsital NHS Foundation Trust—£776,000
Oxford University Hospitals NHS FT—£776,000
The Newcastle upon Tyne Hospitals NHS Foundation Trust—£776,000
University Hospitals Southampton—£776,000
North Manchester General Hospital—£776,000
University Hospitals Bristol and Weston NHS Foundation Trust—£1,036,000
AlderHey Children's NHS FT—£776,000
Great Ormond Street Hospital—£753,000
Guy's and St Thomas' NHS Foundation Trust (SME)—£753,000
University Hospitals Bristol and Weston NHS Foundation Trust—£753,000
University Hospitals of North Staffordshire NHS Trust—£753,000
Sheffield Children's NHS Foundation Trust—£753,000
Leeds Teaching Hopsital NHS Foundation Trust—£753,000
Oxford University Hospitals NHS FT—£753,000
The Newcastle upon Tyne Hospitals NHS Foundation Trust—£753,000
University Hospitals Southampton—£753,000
Sheffield Teaching Hospitals NHS Foundation Trust—£1,036,000
North Manchester General Hospital—£753,000
AlderHey Children's NHS FT—£753,000
Oxford University Hospitals NHS FT—£1,036,000
The Newcastle upon Tyne Hospitals NHS Foundation Trust—£1,036,000
University Hospitals Southampton—£1,036,000
University College London Hospitals NHS Foundation Trust—£1,036,000
St George's University Hospitals NHS Foundation Trust (SME)—£1,036,000
King's College Hospital NHS FT—£1,036,000

Values as the award notice gives them, excluding VAT where stated.

Timeline

  1. Contract notice · notice 053026-2026
  2. Contract award notice · notice 089823-2026

About the buyer

NHS EnglandLast 12 months

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1112

Awards

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From notice 053026-2026 on Find a Tender, first published 4 June 2026, last updated 22 September 2026. We last checked for changes on 28 September 2026.